Abstract Chemoresistance is a prevalent issue in cancer, resulting in a poor prognosis.The transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2), a key regulator in cellular antioxidant responses, is implicated in cell survival, proliferation, and chemoresistance.It represents a promising target for treating Hepatocellular carcino
Guidelines for the management of patients with rheumatoid arthritis (RA) envisage that its therapy should be intensified Flat Caps if it is insufficiently effective; at the same time, reduction of its intensity of treatment may be discussed when the set goal has been successfully achieved.The EULAR guidelines allow for dose reduction and even disco
This article involves the treatment of micro- and nanorange scanning and indentation data for salt rock crystals obtained with help of the scanning microscope Dimension Icon using the mathematical models.It also describes the basic methods of fractal analysis.It shows the effectiveness of the method of minimal covering which is chosen to research t
Due to the unique optical responses induced by vertical atomic asymmetry inside a monolayer, two-dimensional Janus structures have been conceived as promising building blocks for nanoscale optical devices.In this paper, second harmonic generation (SHG) in Janus transition metal chalcogenide oxide monolayers is systematically investigated by the fir
This paper presents an embryo of a literary guide on the Carnation Revolution to be explored for educational historical excursions other than leisure and tourism.We propose a historical trail through the centre of Lisbon, city of the Carnation Revolution, called Walk through the Revolution.The trail aims to reinforce collective memory about the maj